PhD studentship in Biochemistry/Biology at Max Plank Institute

The Laboratory of “Lymphocyte Signaling and Oncoproteome” under Dr. med. Marco Herling at the Department of Internal Medicine I (Chair Prof. Dr. med. M. Hallek) at the University Hospital of Cologne, Germany, is looking for a full-time PhD student in academic cancer research starting her/his position in May – June 2009.


The position is open for a 3-4 year project on the topic of Interrogation of the contribution of TCL1 in molecular cascades of antigen receptor signaling of malignant B-cells in the context of lymphoma initiation and progression.

This work includes in vitro cell line systems, primary cell (co)cultures, and the study of engineered animals, all with respect to protein (kinase) interactions and receptor affinity.

We are looking for a highly motivated candidate with sufficiently practical research experience as well as theoretical background in the above field of lymphocyte cell signaling. Please refrain from applying if you can not prove experience in the above area.


The candidate should have had exposure to a broad variety of techniques in molecular biology and protein biochemistry and have aquired a strong background in immunology.


Our main focus are the mechanisms of oncogenic transformation in lymphocytes to be exploited for clinical applications in the future. Our institution is one of 4 German officially accredited Excellence Centers in Oncology. In addition, we are also part of the new CECAD initiative clustering the most renowned research teams of the Cologne Campus in the field of aging research with exclusive curricula and facilities. Our department is the home of Europe’s largest clinical trial group in chronic lymphocytic leukemia.

We are a young and ambitious 7-person team (2 post-doc’s, 3 PhD students, 1 Research Technician, 1 MD student) embedded in an excellent environment of multiple expertises and collaborations at the Medical School main campus. This 3-4 year degree-granting work in our laboratory will also be part of an enrollment in the Graduate School for Biomedical Sciences (GSfBS) with a multidisciplinary Thesis committee. It would expose the candidate to a variety of experimental methods of protein detection, isolation and biochemistry, as well as techniques in molecular biology and experimental immunology, using cancer models and patient material.Basic requirements for this position are a Diploma / Masters in the natural sciences as well as proficiency in basic methods of molecular biology and cell signaling research. In order to be approved by the GSfBS, the candidate must have completed a single continuous 9 months – 1 year experimental Masters / Diploma work. We will give preference to candidates with additional (extracurricular) under- or postgraduate (after Diploma / Masters) training with proven productivity (publications).The application should comprize a CV including a photograph and undergraduate grades (German Abiturnoten), list of technical expertise, two phone numbers of people providing references, and your contact information. The application deadline is March 31st, 2009. The application process includes written questionnaires and interviews subsequent to the submission of the above requested information.We are looking forward to your application.For further information please contact Dr. M. Herling under +49 221 478-5465 or -5194 or at marco.herling@uk-koeln.de


Or visit our web-site:

http://www.uk-koeln.de/kliniken/innere1/forschung/e_lab_lymphocyte


Signaling Oncoproteome University of Cologne


Website:

http://www.uk-koeln.de/klinik…


Location:

Cologne Medical School Campus, CECAD Campus, GSfBS Campus, Max-Planck Institute
Campus

Expires:
May 18, 2009